Ace's success is placed into jeopardy by Nicky, not only by his reckless, violent, volatile and ruthless behavior, but also by his want to eke out his own gangster fiefdom in Las Vegas. Ace is able to make a success of the casino, which includes the process of the Mafia bosses being able to skim profits off the top, while making the entire business look legitimate to the authorities. Ace's best friend from childhood Nicky Santoro, eventually comes along for the ride, he who the Mafia hires to be Ace and the organization's unofficial protector. Ace can do the job, applying for his gaming license despite his past, while having his ever changing job title be anything but running the casino and the actual license getting lost in the never ending process.
In 1975, bookie and expert handicapper Sam Rothstein - Ace to his friends - goes somewhat legitimate when the Chicago based Italian Mafia hires him to run the Tangiers Casino on the Las Vegas Strip.